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Inventi Impact: Planta Activa

Articles

  • Inventi:ppa/18557/16
    Beninese Medicinal Plants as a Source of Antimycobacterial Agents: Bioguided Fractionation and In -\nvitro Activity of Alkaloids Isolated from Holarrhena floribunda Used in Traditional Treatment of\nBuruli Ulcer
    01-Jan-1970 Research 2016 : January - March
    Achille Yemoa, Joachim Gbenou, Dissou Affolabi, Mansourou Moudachirou, Andre Bigot, Severin Anagonou, Francoise Portaels, Anandi Martin, Joelle Quetin-Leclercq

    Buruli ulcer (BU) imposes a serious economic burden on affected households and on health systems that are involved in diagnosing\nthe disease and treating patients. Research is needed to find cost-effective therapies for this costly disease. Plants have always been\nan important source of new pharmacologically active molecules. Consequently we decided to undertake the study of plants used\nin traditional treatment of BU in Benin and investigate their antimycobacterial activity as well as their chemical composition.\nExtracts from forty-four (44) plant species were selected on account of reported traditional uses for the treatment of BU in Benin\nand were assayed for antimycobacterial activities. Crude hydroethanolic extract from aerial parts of Holarrhena floribunda (G.Don)\nT. Durand and Schinz was found to have significant antimycobacterial activity a gains M. ulcerans (MIC = 125

    How to Cite this Article
    CC Compliant Citation: Achille Yemoa, Joachim Gbenou, Dissou Affolabi, et al., â??Beninese Medicinal Plants as a Source of\nAntimycobacterial Agents: Bioguided Fractionation and In Vitro Activity of Alkaloids Isolated from Holarrhena floribunda Used in\nTraditional Treatment of Buruli Ulcer,â? BioMed Research International, vol. 2015, Article ID 835767, 5 pages, 2015.\ndoi:10.1155/2015/835767, http://creativecommons.org/licenses/by/3.0).
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